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Pet foodSo-so

Ethoxyquin

الإيثوكسيكين

Synthetic antioxidant preservative · CAS: 91-53-2

The VerdictSo-so

Permitted in the US, suspended in the EU - and often hidden

Why this verdict

Most contested pet-food preservative. FDA permits (animal feed max 150 ppm; CVM-requested voluntary 75 ppm in dog food, 1997). EU SUSPENDED authorisation for all species (Reg (EU) 2017/962) on EFSA data gaps + p-phenetidine impurity - not proof of harm. Only verified effect: hepatic protoporphyrin IX buildup + elevated liver enzymes (dogs more sensitive than rats); contested owner-reported harms unproven. Often present undeclared via fish meal. Caution (not avoid): permitted, no causal harm established at use levels.

What It Is

A synthetic antioxidant; also used to stabilise fish meal.

WTF Fact

This is the most debated preservative in pet food. The verified facts: it builds up a pigment (protoporphyrin) and raises liver enzymes in some animals - dogs are more sensitive than rats - though no clear illness has been pinned to those changes. The US FDA still permits it but asked makers to halve the dog-food limit to 75 ppm back in 1997; the EU suspended it entirely in 2017 over data gaps and an impurity, not proof of harm. The catch: it’s often added to fish meal before it reaches the factory, so a fish-based food can contain it without “ethoxyquin” on the label. If it’s listed, it must say “ethoxyquin, a preservative.” Plenty of brands have dropped it; the facts are mixed and the choice is yours.

Evidence & Status

For Dogs & Cats

Dogs

So-so

Cats

So-so

AAFCO / FDA status

FDA-approved feed antioxidant (max 150 ppm; CVM voluntary 75 ppm in dog food, 1997); must be declared ("ethoxyquin, a preservative"). EU suspended 2017 (Reg (EU) 2017/962).

Applies to

both (dog more sensitive)

Halal Status: Halal

Synthetic; permissible.

Standard: MS 1500:2019; GSO 2055-1; JAKIM e-SMAF

Also Known As

EMQ · ethoxyquine · santoquin

Primary Source

FDA CVM, "Labeling and Use of Ethoxyquin in Animal Feed" - approved feed antioxidant with tolerance and mandatory label statement; 1997 CVM requested voluntary reduction to 75 ppm in dog food after liver-enzyme/protoporphyrin findings; only verified effect = hepatic protoporphyrin IX buildup + elevated liver enzymes, no known health consequence.

Evidence, not medical advice. You decide.

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