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SupplementsSo-so

Cinnamon (Cassia / Coumarin)

القرفة (الكاسيا / الكومارين)

Traditional botanical / spice · CAS: n/a (cassia bark; coumarin CAS 91-64-5)

The VerdictSo-so

On your food, cinnamon is fine - sprinkle away. The caution is specifically for taking CASSIA cinnamon as a daily, high-dose supplement, because cassia is loaded with coumarin, a natural compound that can stress the liver. The numbers are striking: the tolerable daily coumarin limit is about 6–7 mg for an adult, yet a single teaspoon of cassia can carry 8.5–15.5 mg - so a daily cassia habit can quietly exceed the limit, and rare liver-injury cases have been reported. The fix is simple and is the single most useful thing ORIA can tell you: if you use cinnamon every day, switch to CEYLON ('true') cinnamon, which is essentially coumarin-free. One myth to drop: cinnamon's coumarin is NOT a blood thinner - that's a different, synthetic compound (warfarin). The real issue is the liver.

Why this verdict

As a kitchen spice, cinnamon is fine - the caution is specifically about CASSIA cinnamon taken as a DAILY, HIGH-DOSE SUPPLEMENT (for blood sugar or weight loss), because cassia is naturally high in COUMARIN, a compound that can harm the liver. Most supermarket and supplement 'cinnamon' is cassia (Chinese/Indonesian/Saigon); Ceylon ('true') cinnamon is essentially coumarin-free. EFSA set a tolerable daily intake for coumarin of 0.1 mg/kg body weight (about 6–7 mg/day for an adult), derived from a liver-toxicity NOAEL; independent testing found a single teaspoon (~2.5 g) of cassia cinnamon contains roughly 8.5–15.5 mg of coumarin - i.e. one teaspoon a day can already exceed the limit, and concentrated cassia supplements more so. There are documented, if rare and idiosyncratic, reversible cases of cinnamon-associated liver injury. Graded CAUTION, consistent with ORIA's rare-hepatotoxicity precedent - and a stronger, more mechanistic case than most, because the dose-toxicity link is well characterised and the common cassia product routinely crosses the safety limit. The single most useful, actionable fact ORIA can give is the species swap: choose CEYLON cinnamon for any regular/high-dose use. NOTE: the 'coumarin' in cinnamon is NOT an anticoagulant - it is not the same as the compound warfarin (a synthetic 4-hydroxycoumarin) - so the popular 'cinnamon thins your blood' claim is a misconception; the real concern is the liver.

What It Is

Kitchen cinnamon is fine; the caution is DAILY HIGH-DOSE CASSIA supplements, which are high in coumarin (liver risk). EFSA coumarin TDI ~6–7 mg/day adult; 1 tsp cassia ≈ 8.5–15.5 mg - easily exceeded. Rare reversible liver-injury cases. Fix: use CEYLON ('true') cinnamon for regular use. (Coumarin ≠ anticoagulant.) Graded caution.

WTF Fact

Cinnamon is the spice everyone assumes is harmless, and as a flavouring on your oats or in your coffee, it essentially is. ORIA's caution applies to a specific use: taking cassia cinnamon as a daily, concentrated SUPPLEMENT, usually marketed for blood sugar or weight loss. The pivot point is a compound called coumarin. There are two main commercial cinnamons, and they are not interchangeable: cassia cinnamon (the cheap, common one - Chinese, Indonesian or Saigon) is naturally HIGH in coumarin, while Ceylon or 'true' cinnamon (Cinnamomum verum) contains almost none. Coumarin can cause liver injury: European food-safety authorities set a tolerable daily intake of 0.1 mg per kilogram of body weight - roughly 6 to 7 milligrams a day for an adult - based on liver toxicity in animal studies. Independent laboratory testing found that a single teaspoon of cassia cinnamon contains somewhere between about 8.5 and 15.5 milligrams of coumarin, so even a teaspoon a day of cassia can put you over the limit, and a concentrated cassia capsule taken daily pushes further. On top of the regulatory limit, there are documented - though rare and idiosyncratic - case reports of reversible acute liver injury (jaundice, raised liver enzymes) attributed to cinnamon, resolving once it was stopped. That combination of a clear dose-toxicity mechanism plus real, if uncommon, human cases is why ORIA grades it caution rather than okay - a more concrete liver case than several botanicals it already flags. The good news is that the remedy is trivially simple and worth repeating: if you use cinnamon regularly or in supplement doses, choose CEYLON cinnamon, which is essentially coumarin-free; reserve cassia for occasional culinary use. A quality note: some products labelled 'Ceylon' have tested as cassia, so buy from a reputable source. Finally, a myth to retire - the coumarin in cinnamon is NOT an anticoagulant; it is chemically distinct from the blood-thinning compound warfarin, so the 'cinnamon thins your blood' line is wrong; the genuine concern is the liver. Verdict: love it on your food, but if you're taking cinnamon daily or as a supplement, switch to Ceylon and keep cassia for the spice rack.

Evidence & Status

EU Status

Permitted spice/food & food supplement; several EU bodies advise limiting coumarin intake (TDI 0.1 mg/kg bw/day).

US · FDA Status

Permitted as spice/food/dietary supplement (GRAS as a spice).

Intake & Safety

Upper limit (UL)

Coumarin tolerable daily intake (EFSA) 0.1 mg/kg bw/day (~6–7 mg/day adult); ~1 tsp cassia (~2.5 g) ≈ 8.5–15.5 mg coumarin (can exceed the limit). Ceylon cinnamon: coumarin negligible.

Interactions

ADDITIVE HYPOGLYCEMIA with diabetes agents (cinnamon is taken for blood sugar); caution stacking high-dose cassia with other hepatotoxic agents or alcohol. (Note: cinnamon's coumarin is NOT an anticoagulant - distinct from warfarin.)

Third-party testing

useful (species verification: confirm Ceylon vs cassia; coumarin content)

Halal Status: Halal

Cinnamon is a plant bark - halal. Only the capsule shell (gelatin vs plant) is a halal check for supplement forms.

Standard: Plant bark — halal; confirm capsule shell per MS 1500:2019.

Worth Knowing

Allergen: Possible spice/contact sensitivity in sensitive individualsUse caution for childrenUse caution in pregnancy

Also Known As

cinnamon · cassia cinnamon · Chinese cinnamon · Cinnamomum cassia / aromaticum / burmannii / loureiroi · coumarin · qirfa · darseen · (vs Ceylon/'true' cinnamon = Cinnamomum verum/zeylanicum)

Primary Source

Coumarin-Induced Hepatotoxicity: A Narrative Review (PMC9783661): cassia cinnamon (Cinnamomum cassia) contains substantial coumarin (~2.23 mg/g dry wt) vs negligible in true/Ceylon cinnamon (<0.01 mg/g); EFSA derived a coumarin TDI from a liver-toxicity NOAEL of 10 mg/kg bw/day; coumarin produces reactive metabolites and rare idiosyncratic clinically apparent liver injury in humans.

Evidence, not medical advice. You decide.

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